Bibliography on larval excretion/secretion (LES)

Abdel-Samad, M. R. K. (2019). Antiviral and virucidal activities of Lucilia cuprina maggots’ excretion/secretion (Diptera: Calliphoridae): first work. Heliyon, 5(11), e02791. https://doi.org/10.1016/j.heliyon.2019.e02791

Abdel-Samad, M. R. K., Taher, F. A., Shehata, M., Shama, N. M. A., Mostafa, A., Ali, M. A., & Ibrahim, I. H. (2022). Strong anti-SARS-CoV-2 activity of Lucilia cuprina maggots’ excretion/secretion and its effect on viral entry and notch pathway in vitro: First work. Journal of Applied Pharmaceutical Science, 12,(7), 122–130. https://doi.org/10.7324/JAPS.2022.120713

Abdel-Samad, M. R., & Taher, F. A. (2021). Wound healing and antibacterial activities of water-soluble chitosan nanoparticles and excretion/secretion as a natural combination from medicinal maggots, Lucilia cuprina. Journal of Bioactive and Compatible Polymers, 36(6), 510–519. https://doi.org/10.1177/08839115211053921

Alipour, H., Raz, A., Dinparast Djadid, N., & Zakeri, S. (2019). Expression of a New Recombinant Collagenase Protein of Lucilia Sericata in SF9 Insect Cell as a Potential Method for Wound Healing. Iranian Journal of Biotechnology, 17(4), e2429. https://doi.org/10.30498/IJB.2019.92707

Alipour, H., Raz, A., Zakeri, S., & Dinparast Djadid, N. (2016). Therapeutic applications of collagenase (metalloproteases): A review. Asian Pacific Journal of Tropical Biomedicine, 6(11), 975–981. https://doi.org/10.1016/j.apjtb.2016.07.017

Armstrong, D. G., Rowe, V. L., D’Huyvetter, K., & Sherman, R. A. (2020). Telehealth‐guided home‐based maggot debridement therapy for chronic complex wounds: Peri‐ and post‐pandemic potential. International Wound Journal, 17(5), 1490–1495. https://doi.org/10.1111/iwj.13425

Aubernon, C., Hedouin, V., & Charabidze, D. (2019). The maggot, the ethologist and the forensic entomologist: Sociality and thermoregulation in necrophagous larvae. Journal of Advanced Research, 16, 67–73. https://doi.org/10.1016/j.jare.2018.12.001

Babe, L. M., Goedegebuur, F., Ghirnikar, R., Gu, X., Kolkman, M., & Yao, J. (2020). Metalloproteases (Patent 10696958). https://patents.google.com/patent/US10696958B2/en?oq=10696958

Barnes, K. M., Gennard, D. E., & Dixon, R. A. (2010). An assessment of the antibacterial activity in larval excretion/secretion of four species of insects recorded in association with corpses, using Lucilia sericata Meigen as the marker species. Bulletin of Entomological Research, 100(6), 635–640. https://doi.org/10.1017/S000748530999071X

Bexfield, A., Bond, A. E., Morgan, C., Wagstaff, J., Newton, R. P., Ratcliffe, N. A., Dudley, E., & Nigam, Y. (2010). Amino acid derivatives from Lucilia sericata excretions/secretions may contribute to the beneficial effects of maggot therapy via increased angiogenesis. The British Journal of Dermatology, 162(3), 554–562. https://doi.org/10.1111/j.1365-2133.2009.09530.x

Bexfield, A., Bond, A. E., Roberts, E. C., Dudley, E., Nigam, Y., Thomas, S., Newton, R. P., & Ratcliffe, N. A. (2008). The antibacterial activity against MRSA strains and other bacteria of a <500Da fraction from maggot excretions/secretions of Lucilia sericata (Diptera: Calliphoridae). Microbes and Infection, 10(4), 325–333. https://doi.org/10.1016/j.micinf.2007.12.011

Bexfield, A., Nigam, Y., Thomas, S., & Ratcliffe, N. A. (2004). Detection and partial characterization of two antibacterial factors from the excretions/secretions of the medicinal maggot Lucilia sericata and their activity against methicillin-resistant Staphylococcus aureus (MRSA). Microbes and Infection, 6(14), 1297–1304. https://doi.org/10.1016/j.micinf.2004.08.011

Bian, H., Yang, Q., Ma, T., Li, W., Duan, J., Wei, G., Wu, X., Mu, F., Lin, R., Wen, A., & Xi, M. (2017). Beneficial effects of extracts from Lucilia sericata maggots on burn wounds in rats. Molecular Medicine Reports, 16(5), 7213–7220. https://doi.org/10.3892/mmr.2017.7566

Blenkiron, C., Tsai, P., Brown, L. A., Tintinger, V., Askelund, K. J., Windsor, J. A., & Phillips, A. R. (2015). Characterization of the small RNAs in the biomedically important green-bottle blowfly Lucilia sericata. PloS One, 10(3), e0122203. https://doi.org/10.1371/journal.pone.0122203

Bohova, J., Majtan, J., Majtan, V., & Takac, P. (2014). Selective Antibiofilm Effects of Lucilia sericata Larvae Secretions/Excretions against Wound Pathogens. Evidence-Based Complementary and Alternative Medicine, 2014, 1–9. https://doi.org/10.1155/2014/857360

Brown, A. W. A. (1936). The Excretion of Ammonia and Uric Acid During The Larval Life of Certain Muscoid Flies. Journal of Experimental Biology, 13(2), 131–139. https://doi.org/10.1242/jeb.13.2.131

Cazander, G., Pritchard, D. I., Nigam, Y., Jung, W., & Nibbering, P. H. (2013). Multiple actions of Lucilia sericata larvae in hard-to-heal wounds: Larval secretions contain molecules that accelerate wound healing, reduce chronic inflammation and inhibit bacterial infection. BioEssays: News and Reviews in Molecular, Cellular and Developmental Biology, 35(12), 1083–1092. https://doi.org/10.1002/bies.201300071

Cazander, G., van de Veerdonk, M. C., Vandenbroucke-Grauls, C. M. J. E., Schreurs, M. W. J., & Jukema, G. N. (2010). Maggot excretions inhibit biofilm formation on biomaterials. Clinical Orthopaedics and Related Research, 468(10), 2789–2796. https://doi.org/10.1007/s11999-010-1309-5

Cazander, G., van Veen, K. E. B., Bernards, A. T., & Jukema, G. N. (2009). Do maggots have an influence on bacterial growth? A study on the susceptibility of strains of six different bacterial species to maggots of Lucilia sericata and their excretions/secretions. Journal of Tissue Viability, 18(3), 80–87. https://doi.org/10.1016/j.jtv.2009.02.005

Cazander, G., van Veen, K. E. B., Bouwman, L. H., Bernards, A. T., & Jukema, G. N. (2009). The influence of maggot excretions on PAO1 biofilm formation on different biomaterials. Clinical Orthopaedics and Related Research, 467(2), 536–545. https://doi.org/10.1007/s11999-008-0555-2

Constable, S. A. (1994). A Comparison of Proteases Produced by Larvae of Lucilia cuprina (Wiedemann), L. sericata (Meigen), Calliphora augur (F.) and C. stygia (F.) (Diptera: Calliphoridae). Australian Journal of Entomology, 33(3), 203–210. https://doi.org/10.1111/j.1440-6055.1994.tb01218.x

Cuervo, P., Mesquita-Rodrigues, C., d’Avila Levy, C. M., Britto, C., Pires, F. A., Gredilha, R., Alves, C. R., & Jesus, J. B. de. (2008). Serine protease activities in Oxysarcodexia thornax (Walker) (Diptera: Sarcophagidae) first instar larva. Memórias Do Instituto Oswaldo Cruz, 103(5), 504–506. https://doi.org/10.1590/S0074-02762008000500018

Cupp, M. S., Zhang, D., & Cupp, E. W. (2005). Protein from horn fly saliva that disrupts hemostasis (Canada Patent CA2546665A1). https://patents.google.com/patent/CA2546665A1/en

Daeschlein, G., Mumcuoglu, K. Y., Assadian, O., Hoffmeister, B., & Kramer, A. (2007). In vitro Antibacterial Activity of Lucilia sericata Maggot Secretions. Skin Pharmacology and Physiology, 20(2), 112–115. https://doi.org/10.1159/000097983

Davis, R. J., Belikoff, E. J., Dickey, A. N., Scholl, E. H., Benoit, J. B., & Scott, M. J. (2021). Genome and transcriptome sequencing of the green bottle fly, Lucilia sericata, reveals underlying factors of sheep flystrike and maggot debridement therapy. Genomics, 113(6), 3978–3988. https://doi.org/10.1016/j.ygeno.2021.10.003

Díaz-Roa, A., Patarroyo, M. A., Bello, F. J., & Da Silva, P. I. (2018). Sarconesin: Sarconesiopsis magellanica Blowfly Larval Excretions and Secretions With Antibacterial Properties. Frontiers in Microbiology, 9. https://www.frontiersin.org/article/10.3389/fmicb.2018.02249

Durdle, A., Mitchell, R. J., & van Oorschot, R. A. H. (2016). The Food Preferences of the Blow Fly Lucilia cuprina Offered Human Blood, Semen and Saliva, and Various Nonhuman Foods Sources. Journal of Forensic Sciences, 61(1), 99–103. https://doi.org/10.1111/1556-4029.12912

El-Bassiony, G., & Stoffolano, J. (2016). In vitro antimicrobial activity of maggot excretions/secretions of Sarcophaga (Liopygia) argyrostoma (Robineau-Desvoidy). African Journal of Microbiology Research, 10, 1036–1043. https://doi.org/10.5897/AJMR2016.8102

Eltablawy, S. Y., & Amin, M. M. (2011). Evaluation of Anti-adherent Activity of Excretions of Irradiated Lucilia sericata Maggot and Certain Essential Oils against Some Pathogenic Bacterial Strains. Egyptian Journal of Radiation Sciences and Applications, 24(1), 117–128. https://doi.org/10.21608/ejrsa.2011.1459

Evans, R., Dudley, E., & Nigam, Y. (2015). Detection and partial characterization of antifungal bioactivity from the secretions of the medicinal maggot, Lucilia sericata. Wound Repair and Regeneration: Official Publication of the Wound Healing Society [and] the European Tissue Repair Society, 23(3), 361–368. https://doi.org/10.1111/wrr.12287

Fairlamb, D. M., Kelety, B., Bachert, A., Scholtissek, A., Jones, R. D., Davis, S. C., & Kirsner, R. S. (2023). Preliminary evidence supporting a new enzymatic debridement product for use in chronic wounds. International Wound Journal, 20(6), 2095–2104. https://doi.org/10.1111/iwj.14079

Fleischmann, W. (2003). Method and device for rearing insects, especially for obtaining a secretion from fly larvae for therapeutic application (Patent 6557487). https://patents.google.com/patent/US6557487B1/en?oq=6557487

Fleischmann, W. (2005). Method and device for rearing insects, especially for obtaining secretion from fly larvae for therapeutic application (Patent 6863022). https://patents.google.com/patent/US6863022B2/en?oq=6863022

Frank, G. R., Hunter, S. W., & Wallenfels, L. (1999). Ectoparasite saliva proteins and apparatus to collect such proteins (Patent 5927230). https://patft.uspto.gov/netacgi/nph-Parser?Sect2=PTO1&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&d=PALL&RefSrch=yes&Query=PN%2F5927230

Franta, Z., Vogel, H., Lehmann, R., Rupp, O., Goesmann, A., & Vilcinskas, A. (2016). Next Generation Sequencing Identifies Five Major Classes of Potentially Therapeutic Enzymes Secreted by Lucilia sericata Medical Maggots. BioMed Research International, 2016, 8285428. https://doi.org/10.1155/2016/8285428

Garzon, L. R., Fracasso, M., Viana, A. R., Giacometi, M., Samoel, G. V. A., Souza, L., Baldissera, M. D., Petry, L. dos S., Krause, L. M. F., & Monteiro, S. G. (2021). Atividade in vitro da secreção de Lucilia cuprina frente à Leishmania amazonensis, Ttrypanosoma cruzi e linhagens celulares / In vitro activity of larval secretions from Lucilia cuprina against Leishmania amazonensis, Trypanosoma cruzi and cell lines. Brazilian Journal of Development, 7(8), 82837–82858. https://doi.org/10.34117/bjdv7n8-475

Gasz, N. E., Geary, M. J., Doggett, S. L., & Harvey, M. L. (2021). Bacterial association observations in Lucilia sericata and Lucilia cuprina organs through 16S rRNA gene sequencing. Applied Microbiology and Biotechnology, 105(3), 1091–1106. https://doi.org/10.1007/s00253-020-11026-8

Gazi, U., Taylan‐Ozkan, A., & Mumcuoglu, K. Y. (2021). The effect of Lucilia sericata larval excretion/secretion ( ES ) products on cellular responses in wound healing. Medical and Veterinary Entomology, 35(3), 257–266. https://doi.org/10.1111/mve.12497

Giacaman, A. G., Styliari, I. D., Taresco, V., Pritchard, D., Alexander, C., & Rose, F. R. A. J. (2022). Development of bioactive electrospun scaffolds suitable to support skin fibroblasts and release Lucilia sericata maggot excretion/secretion. SN Applied Sciences, 4(12), 331. https://doi.org/10.1007/s42452-022-05209-3

Giglioti, R., Guimarães, S., Oliveira-Sequeira, T. C. G., David, E. B., Brito, L. G., Huacca, M. E. F., Chagas, A. C. S., & Oliveira, M. C. S. (2016). Proteolytic activity of excretory/secretory products of Cochliomyia hominivorax larvae (Diptera: Calliphoridae). Pesquisa Veterinária Brasileira, 36(8), 711–718. https://doi.org/10.1590/S0100-736X2016000800006

Gomes, G., Köberle, R., Von Zuben, C. J., & Andrade, D. V. (2018). Droplet bubbling evaporatively cools a blowfly. Scientific Reports, 8(1), Article 1. https://doi.org/10.1038/s41598-018-23670-2

Harris, L. G. (2009). Disruption of Staphylococcus epidermidis biofilms by medicinal maggot Lucilia sericata excretions/secretions (Patent US20110008402A1). https://patents.google.com/scholar/10449277235929420400

Harris, L. G., Bexfield, A., Nigam, Y., Rohde, H., Ratcliffe, N. A., & Mack, D. (2009). Disruption of Staphylococcus Epidermidis Biofilms by Medicinal Maggot Lucilia Sericata Excretions/Secretions. The International Journal of Artificial Organs, 32(9), 555–564. https://doi.org/10.1177/039139880903200904

Hassan, M. I., Amer, M. S., Hammad, K. M., & Zidan, M. M. (2016). Antimicrobial Activity for Excretion and Secretion of the Greenbottle Fly Larvae Lucilia Sericata (meigen) (diptera: Calliphoridae). Journal of the Egyptian Society of Parasitology, 46(1), 179–184. https://doi.org/10.12816/0026163

Honda, K. (2008). Defensive potential of components of the larval osmeterial secretion of papilionid butterflies against ants. Physiological Entomology, 8, 173–179. https://doi.org/10.1111/j.1365-3032.1983.tb00346.x

Honda, K., Okamoto, K., Mochida, Y., Ishioka, K., Oka, M., Maesato, K., Ikee, R., Moriya, H., Hidaka, S., Ohtake, T., Doi, K., Fujita, T., Kobayashi, S., & Noiri, E. (2011). A novel mechanism in maggot debridement therapy: Protease in excretion/secretion promotes hepatocyte growth factor production. American Journal of Physiology-Cell Physiology, 301(6), C1423–C1430. https://doi.org/10.1152/ajpcell.00065.2011

Horobin, A. J., Shakesheff, K. M., & Pritchard, D. I. (2005). Maggots and wound healing: An investigation of the effects of secretions from Lucilia sericata larvae upon the migration of human dermal fibroblasts over a fibronectin-coated surface. Wound Repair and Regeneration, 13(4), 422–433. https://doi.org/10.1111/j.1067-1927.2005.130410.x

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Isabela Avila-Rodríguez, M., Meléndez-Martínez, D., Licona-Cassani, C., Manuel Aguilar-Yañez, J., Benavides, J., & Lorena Sánchez, M. (2020). Practical context of enzymatic treatment for wound healing: A secreted protease approach (Review). Biomedical Reports, 13(1), 3–14. https://doi.org/10.3892/br.2020.1300

Jafari, A., Babajani, A., Sarrami Forooshani, R., Yazdani, M., & Rezaei-Tavirani, M. (2022). Clinical Applications and Anticancer Effects of Antimicrobial Peptides: From Bench to Bedside. Frontiers in Oncology, 12. https://www.frontiersin.org/article/10.3389/fonc.2022.819563

Jiang, K., Sun, X., Wang, W., Liu, L., Cai, Y., Chen, Y., Luo, N., Yu, J., Cai, D., & Wang, A. (2012). Excretions/secretions from bacteria-pretreated maggot are more effective against Pseudomonas aeruginosa biofilms. PloS One, 7(11), e49815. https://doi.org/10.1371/journal.pone.0049815

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